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It happens because the dye is excreted unchanged by the kidneys

Rodriguez, M.C., Margos, G., Compton, H., Ku, M., Lanz, H., Rodriguez, M.H

Metab Brain Dis 29:1936 Morris G, Anderson G, Maes M (2017a) Hypothalamic-pituitary-adrenal hypofunction in myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) as a consequence of activated immune-inflammatory and oxidative and nitrosative pathways